General Standard for Contaminants and Toxins in Food and Feed (Codex Stan 193-1995)
Chloropropanols
| Reference to JECFA | 57 ( 2002 ) , 41 ( 1993 ) , 67 ( 2007 ) |
| Toxicological guidance value | PMTDI 0.002 mg/kg bw (2001, for 3-chloro-1,2-propanediol); maintained in 2006. Establishment of tolerable intake was considered to be inappropriate for 1,3-dichloro-2-propanol because of the nature of the toxicity (tumorogenic in various organs in rats and the contaminant can interact with chromosomes and/or DNA). BMDL 10 cancer, 3.3 mg/kg bw/day (for 1,3-dichloro-2-propanol); MOE, 65 000 (general population), 2 400 (high level intake, including young children). |
| Contaminant definition | 3-MCPD |
| Synonyms | Two substances are the most important members of this group: 3-monochloropropane-1,2-diol (3-MCPD, also referred to as 3-monochloro-1,2- propanediol) and 1,3-dichloro-2-propanol (1,3-DCP). |
| Related code of practice | Code of Practice for the Reduction of 3-Monochloropropane-1,2-diol (3-MCPD) during the Production of Acid-Hydrolyzed Vegetable Protein (Acid-HVPs) and Products that Contain Acid- HVPs (CAC/RCP 64-2008) |
| Commodity/Product Name | Maximum Level (ML) mg/kg | Portion of the Commodity/Product to which the ML/GL applies | Notes/Remarks |
|---|---|---|---|
| Liquid condiments containing acid hydrolyzed vegetable proteins | The ML does not apply to naturally fermented soy sauce. |